Brand Name : Contrave

Generic Name : Naltrexone hcl and Bupropion hcl

Drug Class : Opioid Antagonists

Dosage Strength : 8 mg/90 mg

Packaging : Packaging is fast, safe and secure and will be delivered directly to your doorstep.


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  • CONTRAVE is a prescription medicine which contains 2 medicines (naltrexone and bupropion) that may help some obese or overweight adults, who also have weight related medical problems, lose weight and keep the weight off.
  • CONTRAVE should be used with a reduced calorie diet and increased physical activity.


Side Effects

  • Seizures. There is a risk of having a seizure when you take CONTRAVE. The risk of seizure is higher in people who:
  • take higher doses of CONTRAVE
  • have certain medical conditions
  • take CONTRAVE with certain other medicines


  • Risk of opioid overdose. One of the ingredients in CONTRAVE (naltrexone) can increase your chance of having an opioid overdose if you take opioid medicines while taking CONTRAVE.
    You can accidentally overdose in 2 ways:
  • Naltrexone blocks the effects of opioids, such as heroin, methadone or opioid pain medicines. Do not take large amounts of opioids, including opioid-containing medicines, such as heroin or prescription pain pills, to try to overcome the opioid-blocking effects of naltrexone. This can lead to serious injury, coma, or death.
  • After you take naltrexone, its blocking effect slowly decreases and completely goes away over time. If you have used opioid street drugs or opioid-containing medicines in the past, using opioids in amounts that you used before treatment with naltrexone can lead to overdose and death. You may also be more sensitive to the effects of lower amounts of opioids:
    Your healthcare provider may need to stop treating you with CONTRAVE if you get signs or symptoms of a serious liver problem.

Talk with your healthcare provider to find out if you are at risk for angle-closure glaucoma and to get treatment to prevent it if you are at risk.

After you have gone through detoxification
when your next dose of CONTRAVE is due

  • if you miss a dose of CONTRAVE
  • after you stop CONTRAVE treatment
  • It is important that you tell your family and the people closest to you of this increased sensitivity to opioids and the risk of overdose.

You or someone close to you should get emergency medical help right away if you:

  • have trouble breathing
  • become very drowsy with slowed breathing
  • have slow, shallow breathing (little chest movement with breathing)
  • feel faint, very dizzy, confused, or have unusual symptoms
  • Sudden opioid withdrawal. People who take CONTRAVE must not use any type of opioid (must be opioidfree) including street drugs, prescription pain medicines (including tramadol), cough, cold, or diarrhea medicines that contain opioids, or opioid dependence treatments, buprenorphine or methadone, for at least 7 to 10 days before starting CONTRAVE. Using opioids in the 7 to 10 days before you start taking CONTRAVE may cause you to suddenly have symptoms of opioid withdrawal when you take it. Sudden opioid withdrawal can be severe, and you may need to go to the hospital. Tell your healthcare provider you are taking CONTRAVE before a medical procedure or surgery.
  • Severe allergic reactions. Some people have had a severe allergic reaction to bupropion, one of the ingredients in CONTRAVE. Stop taking CONTRAVE and call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of an allergic reaction:
  • rash
  • itching
  • hives
  • fever
  • swollen lymph glands
  • painful sores in your mouth or around your eyes
  • swelling of your lips or tongue
  • chest pain
  • trouble breathing
  • Increases in blood pressure or heart rate. Some people may get high blood pressure or have a higher heart rate when taking CONTRAVE. Your healthcare provider should check your blood pressure and heart rate before you start taking, and while you take CONTRAVE.
  • Liver damage or hepatitis. One of the ingredients in CONTRAVE, naltrexone can cause liver damage or hepatitis. Stop taking CONTRAVE and tell your healthcare provider if you have any of the following symptoms of liver problems:
    stomach area pain lasting more than a few days
    dark urine
  • yellowing of the whites of your eyes
  • tiredness
  • Manic episodes. One of the ingredients in CONTRAVE, bupropion can cause some people who were manic or depressed in the past to become manic or depressed again.
  • Visual problems (angle-closure glaucoma). One of the ingredients in CONTRAVE, bupropion, can cause some people to have visual problems (angle-closure glaucoma). Signs and symptoms of angle-closure glaucoma may include:
  • eye pain
  • changes in vision
  • swelling or redness in or around the eye
  • Increased risk of low blood sugar (hypoglycemia) in people with type 2 diabetes mellitus who also take medicines to treat their diabetes. Weight loss can cause low blood sugar in people with type 2 diabetes mellitus who also take medicines used to treat type 2 diabetes mellitus (such as insulin or sulfonylureas). You should check your blood sugar before you start taking CONTRAVE and while you take CONTRAVE.

The most common side effects of CONTRAVE include:

  • nausea
  • constipation
  • headache
  • vomiting
  • dizziness
  • trouble sleeping
  • dry mouth
  • diarrhea
    These are not all of the possible side effects of CONTRAVE.


CONTRAVE is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of:

  • 30 kg/m² or greater (obese) or
  • 27 kg/m² or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia).

Limitations Of Use

  • The effect of CONTRAVE on cardiovascular morbidity and mortality has not been established.
  • The safety and effectiveness of CONTRAVE in combination with other products intended for weight loss, including prescription drugs, over-the-counter drugs, and herbal preparations, have not been established.


CONTRAVE is contraindicated in

  • Uncontrolled hypertension
  • Seizure disorder or a history of seizures
  • Use of other bupropion-containing products (including, but not limited to, WELLBUTRIN, WELLBUTRIN SR, WELLBUTRIN XL, APLENZIN and ZYBAN)
  • Bulimia or anorexia nervosa, which increase the risk for seizure
  • Chronic opioid or opiate agonist (e.g., methadone) or partial agonists (e.g., buprenorphine) use, or acute opiate withdrawal
  • Patients undergoing an abrupt discontinuation of alcohol, benzodiazepines, barbiturates, and antiepileptic drugs
  • Concomitant administration of monoamine oxidase inhibitors (MAOI). At least 14 days should elapse between discontinuation of MAOI and initiation of treatment with CONTRAVE. There is an increased risk of hypertensive reactions when CONTRAVE is used concomitantly with MAOIs. Starting CONTRAVE in a patient treated with reversible MAOIs such as linezolid or intravenous methylene blue is also contraindicated
  • Known allergy to bupropion, naltrexone or any other component of CONTRAVE. Anaphylactoid/anaphylactic reactions and Stevens-Johnson syndrome have been reported with bupropion

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Additional information


120 8 mg/90 mg Tablets, 150 8 mg/90 mg Tablets, 60 8 mg/90 mg Tablets, 90 8 mg/90 mg Tablets


As payment methods, we accept Credit cards, Bank Transfers, Western Union, MoneyGram, PayPal, Cash App, Zelle, Venmo, and Cryptocurrency (10% discount for all cryptocurrency payments).

When you are placing the order you will be prompted to choose a payment method and you’ll receive all the necessary information through email.

Shipping & Delivery


Packages are generally dispatched Overnight after receipt of payment and are shipped via fast courier services so the package will be delivered to you within 1 – 2 days from dispatch. You will also receive an email containing the parcel’s tracking number.

No shipping fee is included handling and packing fees, as well as postage costs, is all taken care of by Us.


Items purchased with us can be returned on the following conditions:

Wrong Item Received : If your delivery is incorrect for any reason i.e. an item has been missed from your order or you have received the wrong item then we will automatically replace or refund your order at your request. If you require a refund then you must inform us immediately and not open any of the packages. We will then ask you to return the goods, and upon arrival at our office, we will refund you via your original payment method.

Items Faulty on Arrival : Your items turn out to be faulty on arrival then we also ask that you let us know immediately via our Contact page or email. Items should be returned in their original packaging with any accompanying documentation or accessories. If we can verify the fault at our end then we will issue a replacement to be sent out the very same day. We can also issue a full refund if you wish and your payment will be returned via your original payment method. We will analyze returned goods and if they prove not faulty then we will return the item to you and you will be liable for the return transit costs.

Items Damaged in Transit : If any items have been damaged in transit, we ask that you report it to us immediately upon receipt of the goods. items should be returned in their original packaging complete with accessories and documents. Once received we will issue a replacement item or refund the full value of your order via your original method of payment.

If you change your mind you have simply changed your mind about any item you have ordered and want to return it to us, then in line with the Distance Selling Regulations, you can as long as you return it to us or inform us within the first 7 days of your purchase or receipt of the goods. The products must not be opened, used or tested and they must be returned in the exact same form as which they were received by yourself posted by us. Again, once we have received the product back to us we will issue a full refund for you via your original payment method.

Open Packages on Arrival : your package arrives opened or ripped for any reason then we ask that you return the items if unhappy. Again we will offer you a replacement product or refund via your original payment method whichever you prefer.

6 reviews for Contrave

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